The prevalence of glaucoma in African-derived peoples of the developing world is substantially higher than in non–African-derived populations in developed nations. Two primary factors-a high prevalence of the disease and limited glaucoma-specific health care resource availability-join to create a perfect storm in which the rate of otherwise preventable glaucoma-related blindness greatly exceeds that observed in the developed world. The management of glaucoma in the developing world remains a significant public health challenge. If repeatable, SLT could be a powerful tool for reducing glaucoma-related blindness in this population. Five eyes of 3 subjects had IOP spikes between 5 and 10 mm Hg that resolved without treatment.Ĭonclusions The magnitude and duration of IOP reduction are clinically relevant in individuals from St. Most subjects reported moderate photophobia for 2 to 3 days after SLT only 1 received anti-inflammatory therapy. The 12-month Kaplan-Meier survival rate (≥10% IOP reduction from postwashout baseline) was 77.7%, and 93% of successful subjects experienced IOP levels less than with-medication values. The mean IOP reductions from baseline ranged from 7.3 to 8.3 mm Hg (34.1%-38.8%) in right eyes and from 7.6 to 8.2 mm Hg (36.0%-38.9%) in left eyes through 12 months. Intraocular pressure dropped significantly by the first week and remained in the range of 13 to 14 mm Hg without medical therapy through 12 months in patients deemed successful.
Both eyes demonstrated a prompt and sustained IOP response to SLT therapy. Results Mean (SD) IOP with medical therapy was 17.3 (5.0) mm Hg and 17.5 (4.0) mm Hg in the right and left eyes, respectively, and increased to 21.4 (3.6) mm Hg and 21.1 (3.5) mm Hg, respectively, after washout. Intraocular pressure (IOP) was measured 1 hour 1 week and 1, 3, 6, 9, and 12 months after SLT. Lucia with medically treated primary open-angle glaucoma underwent a 30-day washout, followed by bilateral 360° SLT. Objective To evaluate the efficacy of selective laser trabeculoplasty (SLT) for the treatment of primary open-angle glaucoma in an African-derived population in the developing world. Shared Decision Making and Communication.Scientific Discovery and the Future of Medicine.Health Care Economics, Insurance, Payment.Clinical Implications of Basic Neuroscience.Challenges in Clinical Electrocardiography.
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